Gastro esophageal reflux disease (GERD) is a condition where it causes severe damage to the esophagus due to constant regurgitation of acidic stomach juices. Heartburns, when uncontrolled and untreated, will significantly damage the tissues surrounding the esophagus. Nexium can treat these symptoms and allow the esophagus to heal and as well to prevent further damage to it.
Nexium also prevents ulcers from developing on people that are taking Non-Steroidal anti-inflammatory drugs (NSAIDs) as well as those ulcers caused by stomach bacteria. It functions by decreasing the acidity in the stomach by limiting the production of stomach acids (ATPase) in gastric parietal cells.

•    Nexium is meant to be used for maintenance purposes on people who suffers from heartburn at least twice a weak even if there are proper adjustments done in diet and exercise.
•    This drug does not offer instant relief of heartburn symptoms.
•    It is important to take the drug throughout the intended and prescribed length of time.
•    Know the difference between heartburn and heart attack.  If you feel chest pain and pain spreading to the arm or shoulder and other general ill feeling, contact your doctor right away.
•    Nexium and other proton pump inhibitor drugs are known to cause brittleness of the bone leading to bone fractures in prolonged usage and higher dosage consumption.

Before taking Nexium, check with your doctor especially if you previously have or is currently suffering from the following:
•    Liver disease
•    Low levels of magnesium in the blood
Do not take Nexium if you are allergic to esomeprazole as well as other proton pump inhibitors or any of its ingredients.

The recommended dose of Nexium for the treatment of reflux esophagitis is 40 mg taken once a day for a period of 4-8 weeks. Treatment can be continued with a dose of 20 mg once a day.

To treat GERD (gastro esophageal reflux disease) or heartburn, it is recommended to use a dosage of 20 mg once a day for 2-4 weeks. To treat or prevent ulcers associated with the use of NSAID (non steroidal anti inflammatory drug), we recommend a dose of 20 mg taken once a day.

To treat stomach ulcers caused by Helicobacter pylori in adults, the dose of esomeprazole is 20 mg two times daily in conjunction with amoxicillin 1000 mg two times daily and clarithromycin 500 mg two times a day – for 7 days in all cases.

To treat GERD in children aged 12 months to 11 years, the recommended dose of esomeprazole is 10 mg and 20 mg (according to the child's body weight) taken once a day for 8 weeks.

The esomeprazole tablets should be swallowed, not chewed. The tablet can also be placed in a half glass of water. Stir until it disintegrates. Drink immediately or in the following 30 minutes the liquid containing the small particles of Nexium.
For the full dose to be taken, rinse the glass with water and drink.

The packets contain esomeprazole granules for oral suspension. Empty the entire bag of pellets in a glass containing 15 ml of water, stir and let stand for a few minutes until the mixture thickens. Stir again and drink the mixture in the following 30 minutes.
For the full dose, rinse the glass with water and drink this water.


Important notice: Always consult a doctor before starting treatment with Nexium. Check the leaflet inside for instructions.

Missed doses are considered missed. Leave it and take the next scheduled dosage. Do not overdose to compensate for the missed one. If you remember and still with enough time before the next one, take it, if not then proceed with your regular dosing schedule.

During unexpected and emergency situations, Call for help right away and notify your physician for such matter. You may contact a poison control center or have you taken to the nearest hospital for abrupt treatment; if the person is passed out and not breathing, call 911 or your local emergency response team.

•    Prolonged usage of Nexium may lead to bone fractures, do not attempt to take the medicine longer than the doctor’s prescription.
•    Inform your doctor about all the drugs you are taking before undergoing surgery of any kind.

Consult your doctor if you experience these side effects and they are severe or irritating.

Your pharmacist may be able to give you advice on what to do if these side effects occur: constipation, diarrhea, nausea or vomiting, dizziness, gases, headache, abdominal pain, dryness of the mouth.

Stop taking Nexium G and seek immediate medical attention if the following occur: signs of serious allergic reaction, such as hives, difficulty breathing, swelling of the tongue, face, mouth or throat.

Drug interactions have the tendency to change the effectiveness of either medicine.
•    Cilostazol
•    Clopidogrel
•    Nelfinavir
•    Rifampin
•    St. John’s Wort
•    Amphetamines
•    Atazanavir
•    Digoxin
•    Iron supplements
•    Azole antifungals (Ketoconazole)